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Lymphocyte Trafficking in Health and Disease

Raffaele Badolato
Since the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed to clarifying the key players of immune response in normal physiology and in disease. This book, which deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention, offers a series of contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease.
Autor: Badolato, Raffaele
EAN: 9783764373085
Sprache: Englisch
Seitenzahl: 253
Produktart: Gebunden
Verlag: Birkhäuser Basel Springer, Basel
Untertitel: Ed. by Silvano Sozzani
Schlagworte: Lymphozyten
Größe: 244
Gewicht: 732 g