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Molecular Analysis of B Lymphocyte Development and Activation

The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
EAN: 9783540230908
Sprache: Englisch
Seitenzahl: 260
Produktart: Gebunden
Herausgeber: Singh, Harinder Grosschedl, Rudolf
Verlag: Springer Springer, Berlin Springer Berlin Heidelberg
Schlagworte: Lymphozyten
Größe: 235
Gewicht: 500 g